Key reports and terms at the center of this FH prevalence analysis

I invite the reader to set aside my analysis at any time and initiate an independent reconciliation of the following reports.

“1st Report” “1st Danish Report”

  • 2012: Familial Hypercholesterolemia in the Danish General Population: Prevalence, Coronary Artery Disease, and Cholesterol-Lowering Medication: Marianne Benn, Gerald F. Watts, Anne Tybjaerg-Hansen, and Børge G. Nordestgaard J Clin Endocrin Metab. First published ahead of print August 14, 2012 as doi:10.1210/jc.2012-1563

“Authoritative Report”

  • 2013: Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: Consensus Statement of the European Atherosclerosis Society: Børge G. Nordestgaard, M. John Chapman, Steve E. Humphries, Henry N. Ginsberg, Luis Masana, Olivier S. Descamps, OlovWiklund, Robert A. Hegele, Frederick J. Raal, Joep C. Defesche, AlbertWiegman, Raul D. Santos, Gerald F.Watts, Klaus G. Parhofer, G. Kees Hovingh, PetriT.Kovanen, Catherine Boileau, MaurizioAverna, JanBore´n, EricBruckert, Alberico L. Catapano, Jan Albert Kuivenhoven, Pa¨ivi Pajukanta, Kausik Ray, Anton F. H. Stalenhoef, Erik Stroes, Marja-Riitta Taskinen, and Anne Tybjærg-Hansen, for the European Atherosclerosis Society Consensus Panel European Heart Journal doi:10.1093/eurheartj/eht273

“Corrigendum” (to 1st Danish Report)

  • 2014: Corrigendum to (doi: 10.1210/jc.2014-3926) “Familial Hypercholesterolemia in the Danish General Population: Prevalence, Coronary Artery Disease, and Cholesterol-Lowering Medication” by Marianne Benn, Gerald F. Watts, Anne Tybjærg-Hansen, and Børge G. Nordestgaard jcem.endojournals.org J Clin Endocrinol Metab, December 2014, 99(12):4758–4759

“2nd Danish Report”

  • 2016: Mutations causative of familial hypercholesterolaemia: screening of 98 098 individuals from the Copenhagen General Population Study estimated a prevalence of 1 in 217: Marianne Benn, Gerald F.Watts, Anne Tybjærg-Hansen, and Børge G. Nordestgaard (Note, this includes the supplementary material) 2016: Supplementary Material: How to identify persons with mutations causative for familial hypercholesterolemia: Screening of 98,098 individuals from the Copenhagen General Population Study estimated a prevalence of 1 in 217 European Heart Journal (2016) 37, 1384–1394 doi:10.1093/eurheartj/ehw028

“Regeneron report”

  • 2016: Genetic identification of familial hypercholesterolemia within a single U.S. health care system: Noura Abul-Husn, et al.