What the illusionist sees is not what the audience sees: phenotype versus genotype

Molecular technology shows that the phenotype is more varied than previously thought.  In fact, it would be more appropriate to say that there is no “phenotype.”

With no phenotype for FH, why did phenotyping become the dominant diagnostic strategy for FH?


  • FH = Inherited Hypercholesterolemia.
  • Non-FH = Uninherited Hypercholesterolemia.
  • Not-H = not hypercholesterolemic.
phenotype versus genotype