2011: Founder Effect precludes comparison of the Netherlands’ population with the general population of the USA

Briefly, founder effect results in an unusual prevalence due to specific conditions and cannot thus be representative of a usual, general population like that of the USA. Dutch researchers, using data from the StOEH screening program, found evidence of founder effect in the Netherlands (below left). We will then see some of the same authors, using the same data from StOEH as if representative of the general population (below right). With “gerrymandering,” politicians are able to select precisely those geographical boundaries which favor their own prospects. I’ve coined the word, “geno-mandering,” to illustrate how pharma has funded researchers who have selected precisely those geographical boundaries which favor pharma’s own prospects. (The Danish reports exploit the intermediate founder effect in Denmark, and Regeneron will later take advantage of founder effect among the Amish in its 2016 study.)(Red Flag: the 2014 Dutch report shows up in the 2012 annual report for StOEH: See online PDF: “JAARVERSLAG 2012, STICHTING OPSPORING ERFELIJKE HYPERCHOLESTEROLEMIE.” That is line of research, however, for another time.)

2011: Founder Effect precludes comparison of the Netherlands’ population with the general population of the USA